[Prognostic factors for schizophrenia during first psychotic episode].

OBJECTIVE Reviewing the available literature regarding prognosis for first psychotic episode for developing schizophrenia. METHOD A systematic review of studies which have evaluated prognostic determinants for the first psychotic episode and its relationship to schizophrenia was made. RESULTS 161 articles were reviewed which fulfilled the search criteria and which were adjusted to the purpose of the study. CONCLUSIONS Duration of untreated psychosis (DUP), pre-morbid functioning level, the presence or predominance of negative symptoms, co-morbid consumption of psychoactive substances and psychosocial state were the most influential characteristics for developing schizophrenia in patients presenting a first psychotic episode.